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Pearl Freier on X: "Cell & gene therapies were 2.5x more likely to receive FDA approval after entering Phase 1 than other drug types according to research by the NEWDIGs initiative at Tufts Medical Center h/t @DrPHanley & @alliancerm . @NatRevDrugDisc paper below 1/n https://t.co/DN4k7qWrAt" / X
Andrew Brack on X: "@ArtirKel Parabiosis would argue a large chunk is cell extrinsic. If going all in on cell intrinsic mechanisms, I would prioritize cells that make their own organs/tissues through proliferation-HSCs, and organs that are highly secretory (making the environment) like liver." / X
José Luis Ricón Fernández de la Puente on X: "@chaklaia In every closed system entropy goes up. But we are not closed systems. If need be you can replace cells with externally made cells." / X
How to Practice the Skill of Agency - by Mike
Danny Oak on Substack: "Courage and irresponsibility are two sides of the same coin; only the outcome will reveal which you’ve flipped. I have 3 months to get the same recurring revenue that I did after 17 years at my 9-to-5. Suggestions are welcome! 😎💪😬"
Anu Atluru on Substack: "you are what you re-read"
How to Innovate When Nothing is Defensible Anymore
Cellular alchemy - by Zack Chiang - cellular alchemy
The 23andMe Deal - Cremieux Recueil
Drug Repurposing: How Often Does It Work? | Science | AAAS
pathsofstoicism on Substack: "Repetition isn’t discipline. It’s identity installation. Habits aren’t tasks. They’re evidence. You’re not brushing your teeth. You’re becoming the person who doesn’t miss. You’re not journaling. You’re building a mind that confronts itself daily. You’re not working out. You…"
being too ambitious is a clever form of self-sabotage
Your Health - Function Dashboard
These 3 decisions will determine if you get rich
The New Porn - by Abram Shaffer - This Is a Thesis
you’re a bitch, and that’s why we lack community - by maisa
gor (@goranshbharal): "i don’t think we talk enough about emotional clutter. the way we carry old versions of ourselves, old hopes, old conversations that never ended right. things we don’t need anymore, but can’t quite throw away. we tidy our homes, but not our hearts. maybe peace is just learning ho…"
Home | Substack
Agnes Callard Quotes (Author of Open Socrates)
SOFT GIRL ERA: The rise AND RISE of *soft girls* and hyper-femininity - YouTube
DedCool's Carina Chaz on 'reshaping the way fragrance is defined and experienced' - Glossy
'It’s like a cult': How online perfume communities are shaping the fragrance industry  - Glossy
COVID-19 Showed Who Really Owns Public Spaces. It’s Not the Public | The Walrus
What the Most Famous Book About Trauma Gets Wrong – Mother Jones
On the Arrest of an Autocrat - Columbia Journalism Review
The Lessons of Crypto Media - Columbia Journalism Review
How Hollywood’s Budget Crunch Is Fueling a Canadian Animation Boom
Top Republicans say they're out of the loop as DOGE downsizes Social Security Administration
Shohei Ohtani's World Series Debut Is Great for Baseball | TIME
Why Saquon Barkley Could Be the Real Star of the Super Bowl | TIME
How Food Insecurity is Impacting Voter Apathy - Matter of Fact with Soledad O'Brien
A Dream Deferred: The Broken Promise of New York City Public Housing
Who Gets to Tell the Story of a Lost Music Culture? | The Nation
This Is the Sound of Gentrification | The Nation
A Trump Administration Spreadsheet Leak Put Lives ‘In Danger’: Sources
How will the Smithsonian be affected by Trump's executive order? : NPR
Is Pierre Poilievre too 'in sync' with Donald Trump? | CBC News
Candidates with Extreme Views Welcomed on Poilievre’s Team | The Tyee
Chuck Schumer Is Pushing Young People Away From the Democratic Party With His Toothless Leadership | Teen Vogue
DOJ Launches Probe Into Illinois’ Treatment of People With Disabilities — ProPublica
How Elon Musk, George Soros and Other Billionaires Are Shaping the Most Expensive Court Race in U.S. History — ProPublica
Measles, MAHA, and “soft eugenics” | Science-Based Medicine
Trump's First 100 Days: Corruption, Chaos, and Cruelty
Objectivity Is a Privilege Afforded to White Journalists | The Walrus
Understanding the TDSB’s Budget Woes in Five Charts | The Local
What Would It Take to Rebuild Syria? | The Walrus
Eddington movie review & film summary (2025) | Roger Ebert
A Long Life in Harlem, Made Possible by an Affordable Apartment - The New York Times
The U.S. Has Ordered Mass Deportations Before. Now History Is Repeating Itself. | Teen Vogue
College Campuses Are Closing Their Women’s and LGBTQ+ Centers | Teen Vogue